29th Annual North American Cystic Fibrosis Conference

Oct 7, 2015 ‐ Oct 10, 2015

The synchronized sessions from the 2015 NACFC are NOW AVAILABLE!

Full NACFC registrants have complimentary access to the recordings of the 2015 NACFC Plenary sessions, Symposia and Workshops.

Short Course presentations held on Wednesday, October 7, are also available for an additional fee. To purchase access to the Short Course presentations, click here.

SC01: CLIN-NTR: Eating Behaviors in CF

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SC01: CLIN-NTR: Eating Behaviors in CF

Oct 7, 2015 3:30pm ‐ Oct 7, 2015 7:30pm

Nutrition, weight & BMI are a focus at every CF clinic visit for children, families & the CF care team. Meal time can be stressful for many patients & their families if they are worried about weight & growth. This course will discuss building & maintaining a positive feeding relationship, from infancy through childhood, using child development, nutrition recommendations & the latest research.

Educational Objectives:

1. Identify & discuss behaviors that can promote positive attachment between caregivers & infants to promote a positive feeding environment.
2. Discuss areas for anticipatory guidance & support of caregivers to meet the special nutrition needs of children with CF.
3. Discuss ways to help families with calorie intake goal setting & tracking of progress.

• Scott Powers, Ph.D., ABPP
• Elizabeth Reid, M.S., R.D.N., L.D.N., Clinical Dietitian III

SC02: CLIN: Nuts & Bolts for the Research Coordinator

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SC02: CLIN: Nuts & Bolts for the Research Coordinator

Oct 7, 2015 3:30pm ‐ Oct 7, 2015 7:30pm

This short course will describe the core knowledge & skills research coordinators need to manage the daily activities of a research study while ensuring research subject safety . Organizational strategies will be discussed. Clinical trial outcome measures specific to CF will be discussed & a patient's perspective on clinical trial participation will be presented.

Educational Objectives:

1. Identify common comorbidities seen in medical histories of patients with CF & medications used to treat them.
2. Describe clinical trial outcome measures specific to CF.
3. Employ knowledge gained & identify tools to organize study documents, manage study visits & documentation of data to ensure compliance with GCP.

• Elizabeth Hartigan, M.P.H., R.N., C.R.M., Clinical Research Manager
• Mahrya Johnson, BA, CCRP
• Sandra Hurban, R.N., B.S.N., CCRC
• Kim Simmons, BSN
• Jonathan Spahr, M.D.

SC03: CLIN: Advanced Drug Therapy for CF

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SC03: CLIN: Advanced Drug Therapy for CF

Oct 7, 2015 3:30pm ‐ Oct 7, 2015 7:30pm

The overall goal of this short course to provide CF care providers with the skills & knowledge necessary to provide advanced therapy via an interactive discussion & case-based format. This short course will address the following therapeutic areas: 1. CFTR Modulators & Novel Therapies; 2. Advanced Drug Delivery for an Acute Pulmonary Exacerbation; 3. Nontuberculous Mycobacteria; & 4. ABPA.

Educational Objectives:

1. Describe & evaluate CFTR modulators & new/novel therapies for CF.
2. Discuss & design an evidence-supported continuous/extended infusion beta-lactams & inhaled antibiotics regimen for treating an acute pulmonary exacerbation.
3. Create & assess therapeutic options to treat NTM & ABPA infections in CF.

• Scott Donaldson, M.D., Professor
• David Young, Pharm.D., Professor of Pharmacotherapy
• Kenneth Olivier, M.D., M.P.H., Senior Clinician and Branch Chief
• Jeffery Zobell, Pharm.D., Advanced Clinical Pharmacist

SC04: SW/PSYCH: The Essentials of CF Psychopharmacology

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SC04: SW/PSYCH: The Essentials of CF Psychopharmacology

Oct 7, 2015 3:30pm ‐ Oct 7, 2015 7:30pm

New guidelines from the CF Foundation & European CF Society recommend screening & treatment for depression & anxiety. This course will teach practitioners what they need to know about using psychotropic medication in individuals with CF.

Educational Objectives:

1. Assess anxiety & depression symptoms in individuals with CF before prescribing medication.
2. Review how to use medications recommended by the CFF/ECFS to treat anxiety & depression in individuals with CF.
3. Identify CF-specific factors that may influence the use of psychotropic medication.

• Anna Georgiopoulos, M.D., Assistant Prof. of Psychiatry
• Ahmet Uluer, D.O., M.P.H., Director Adult Cystic Fibrosis Program
• Beth Smith, M.D., Associate Professor of Psychiatry
• Amy Mueller, LCSW
• Stephanie Filigno, Ph.D., Clinical Psychologist, Associate Professor Pediatr
• Deborah Queen, M.D.

SC06: NTR: CF Nutrition 101 - Medical Nutrition Therapy Optimizes CF Outcomes Across the Lifespan, Infants to Adults

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SC06: NTR: CF Nutrition 101 - Medical Nutrition Therapy Optimizes CF Outcomes Across the Lifespan, Infants to Adults

Oct 7, 2015 3:30pm ‐ Oct 7, 2015 7:30pm

This course will include the following topics: age-appropriate recommendations, pediatric feeding behavior, pancreatic enzyme replacement, GI challenges, vitamin/mineral supplementation, pregnancy, CF-related diabetes, & end-of-life nutrition. Available resources will be reviewed as well as current evidence-based literature.

Educational Objectives:

1. Describe the relationship of weight, growth, body mass & optimal nutritional status to CF health outcomes.
2. Summarize GI challenges, recommended vitamin & mineral supplementation & enzyme management throughout the life cycle.
3. Summarize nutrition challenges & management techniques of adults who have CF including CF-related diabetes & pregnancy.

• Ronalee Robert, R.D., C.D.E.
• Suzanne Michel, M.P.H., R.D., L.D.N.
• Catherine M. McDonald, Ph.D., R.D.N., C.S.P., Clinical Dietitian
• Karen M. Maguiness, M.S., R.D., C.S.P., Pediatric Pulmonology Dietitian
• Amanda Leonard, M.P.H., R.D., C.D.E.
• Jillian Sullivan, M.D., University of Vermont Children's Hospital

*** SC05: SW/PSYCH: Advanced Cognitive Behavioral Strategies for Depression & Anxiety

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*** SC05: SW/PSYCH: Advanced Cognitive Behavioral Strategies for Depression & Anxiety

Oct 7, 2015 3:30pm ‐ Oct 7, 2015 7:30pm

This short course is intended for clinicians who have had some exposure to CBT for anxiety and/or depression interested in building on their comfort level & skill to integrate CBT into their practices. The focus will be on CBT interventions that can be introduced in brief sessions with patients & in busy clinic settings. There will be opportunities for hands-on & interactive learning.

Educational Objectives:

1. Practice assessment & case conceptualization using a CBT model.  
2. Practice several essential CBT techniques for the treatment of anxiety & depression.  
3. Identify potential barriers & solutions to the integration of CBT into clinical practice.

• Christina Duncan, Ph.D., Professor
• Deborah Friedman, Ph.D., Psychologist
• Amanda Montgomery, M.S.W., LCSW

SC07: PT & RT: Beginning Airway Clearance for the New CF Team Member

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SC07: PT & RT: Beginning Airway Clearance for the New CF Team Member

Oct 7, 2015 3:30pm ‐ Oct 7, 2015 7:30pm

In this course different types of current evidence-based modern ACTs will be presented, including the Active Cycle of Breathing Technique; Autogenic Drainage; Positive Expiratory Pressure (PEP); Oscillating PEP & external oscillating devices. Also the rationale for techniques, how they affect the pathophysiology of CF together with indications & contraindications & precautions will be discussed.

Educational Objectives:

1. Discuss the different types of evidence-based Modern Airway Clearance Techniques currently available.
2. Describe selection of individiualized airway clearance techniques & situations when they are contraindicated.
3. Discuss the importance of exercise & adherence to therapy across the lifespan in CF.

• Brenda Maud Button, Ph.D., Adjunct Clinical Associate Professor
• Maggie McIlwaine, Ph.D., Physical therapist, British Columbia Children's Hospital

SPQI: Special Session by Invitation Only: Introduction to CF Quality Improvement: The Virtual Improvement Program-Fundamentals 'VIP-F' Launch

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SPQI: Special Session by Invitation Only: Introduction to CF Quality Improvement: The Virtual Improvement Program-Fundamentals 'VIP-F' Launch

Oct 7, 2015 3:30pm ‐ Oct 7, 2015 7:30pm

This comprehensive short course will provide didactic & applied education on practical improvement measurement skills for rapid cycle systems performance improvement in CF care, including: (1) defining measures; (2) linking measures to aims, improvement (change) ideas & the data collection plan; (3) creating run charts, SPC charts; & performance dashboards; & (4) utilizing the CF registry.

Educational Objectives:

1. Demonstrate how to link operationally defined measures to improvement aims & change ideas.
2. Demonstrate how to create a basic data collection plan.
3. Apply measurement skills to create & interpret run charts, XmR charts, p charts & performance dashboards.

• Kris Petren
• Randall S Messier, M.T., M.S.A, PCMH CCE
• Brant Oliver, Ph.D., MS, MPH, APRN-BC

W01: CFTR: Insights Into CFTR Biology

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W01: CFTR: Insights Into CFTR Biology

Oct 8, 2015 10:00am ‐ Oct 8, 2015 11:45am

This workshop is designed to address the cutting-edge research questions to get insights into CFTR biology. It will focus on mutation-specific protein expression, folding, stability & function especially, but not limited for researchers or anyone who is interested in expanding their knowledge on CFTR structure. 

Educational Objectives:

1. Evaluate the current state of mutation-specific therapies & correction of CFTR variants.
2. Describe the role of interdomain interactions on expression, folding, stability & function of CFTR mutations.
3. Identify key modulators that correct trafficking & functional defects. 

• Patrick Thibodeau, Ph.D., Assistant Professor
• Zoltan Bozoky, Ph.D.

W02: APP&D-GMS: New Advances in CF Animal Models

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W02: APP&D-GMS: New Advances in CF Animal Models

Oct 8, 2015 10:00am ‐ Oct 8, 2015 11:45am

This workshop will introduce two rodent models of CF (ΔF508 CFTR rat & a CF mouse expressing human CFTR) & provide new insights into biliary & respiratory CF disease from experiments performed using CF mouse, ferret or pig models. Particular emphasis will be given to evidence demonstrating infection- & inflammation-independent defects in CF airway function.

Educational Objectives:

1. Summarize the advantages/disadvantages of new CF rodent models (the ΔF508 CFTR rat & human CFTR expressing mouse).
2. Explain implications of defective biliary ATP release in CF mice & age-dependent defects in CF ferret alveolar macrophages.
3. Summarize implications of sterile bronchiectasis in CF ferret lungs & inflammation-independent smooth muscle dysfunction in CF pig airways.

• Lane L Clarke, D.V.M.,Ph.D., University of Missouri
• Michel Bagnat, Ph.D.