A leading cause of morbidity and mortality in CF patient populations is chronic respiratory infection. This workshop will present new research on pathogenesis of infections in CF, with a focus on bacterial pathogens in the CF respiratory tract. Abstracts presented will highlight bacterial adaptations to the host environment that promote enhanced virulence and interspecies interactions that influence pathogenesis in the airways.
Discuss the mechanisms utilized by emerging and traditional CF pathogens to establish chronic respiratory disease.
Describe how adaptation to the CF airway environment leads to enhanced virulence of diverse bacterial pathogens.
Identify interactions occurring between bacterial species in the polymicrobial environment of the CF airways that influence pathogenesis of CF respiratory disease.