In this session, we will present data outlining new understanding of inflammatory pathways in CF. We will link inflammation to changes in cellular metabolism and ion channel transport in innate immune cells and bronchial epithelial cells. We will show how these pathways are dysregulated in CF and expand upon potential therapeutic options, which will modify their pro-inflammatory effects.
Define how inflammation influences, and is influenced by, changes in cellular metabolism and ion channel transport in CF immune cells and epithelium.
Relate how these inflammatory pathways may be regulated therapeutically.
Summarize how immune cells and bronchial epithelial cells interact in the CF lung to provide a distinct inflammatory cycle.
Note: Speakers Valerie Urbach and Pauline Bardin's presentations were not recorded at their request.