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33rd Annual North American Cystic Fibrosis Conference


W05--GMS: Cellular Based Models for CF


Oct 31, 2019 9:45am ‐ Oct 31, 2019 11:05am

Description

This session will focus on the most recent advances in the development and use of cellular models for investigating the human Cystic Fibrosis airway epithelium. The session will include talks on both two- and three-dimensional cultures that better recapitulate the native airway epithelium with focus on the application of gene editing, gene delivery, pluripotent stem cells and primary cellular models.

Learning Objectives:

  • Describe the most recent updates in how cellular model systems can be used to understand the pathogenesis of human CF.
  • Define the application of gene editing technologies to better modeling human CF.
  • Discuss the advances in using two and three dimensional models in evaluating CF pathogenesis and therapeutic approaches.

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