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28th Annual North American Cystic Fibrosis Conference

S05: CLIN: The Liver-Gut Axis in CF

Oct 9, 2014 2:00pm ‐ Oct 9, 2014 3:50pm

Standard: $49.99


CF liver disease develops early in childhood and is the second most severe organ complication in CF. This seminar will provide knowledge about the current understanding of CFLD pathogenesis and presents insights about the possible role of intestinal dysbiosis in CFLD. The aim is to identify new areas of CF research and to ignite discussion about possible future treatment strategies for CFLD. Further, a state-of-the-art review about the pathophysiology, clinical presentation and natural course of the disease is directed to all CF caregivers to increase their skills in diagnosing and managing CFLD and complication in CF patients.

Learning Objectives:
  • Describe how altered bile acid secretion and absorption in CF leads to CFLD.
  • Discuss how intestinal dysbiosis in CF may contribute to pathology in CFLD.
  • Apply current knowledge about pathophysiology of CFLD, clinical presentation and complications in managing CF patients with severe CF liver disease.


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