CFF & ECFS have sponsored an International Guidelines Committee on mental health in CF. This session will present the proposed guidelines on screening patients and caregivers for depression and anxiety. Our proposed recommendations include screening individuals with CF ages 12 through adulthood and caregivers of children with CF birth to 17 years. We have recommended specific screening tools, as well as evidence-based psychological and pharmacological interventions. We will present the results of an international survey of health care providers which asked about current screening practices, availability of mental health professionals, and infrastructure needs for implementation.