The overall goal of this short course is to provide CF care providers with the skills and knowledge necessary to provide optimal treatment of difficult to treat infections through an interactive lecture and case-based format. This short course will address the following therapeutic areas: 1. Methicillin Resistant Staphylococcus 2. Nontuberculous mycobacteria 3. Burkholderia cepacia complex, MDR-Pseudomonas aeruginosa, Achromobacter xylosoxidans, Stenotrophomonas maltophilia. 4. Allergic Bronchopulmonary Aspergillosis.