Pulmonary exacerbations are common events in patients with CF but there is no standard approach to treatment. We will review what we have learned from registry data, clinical studies & an observational study of exacerbations & how this will be used in the design of interventional studies of the treatment of exacerbations.
Review the epidemiology of CF pulmonary exacerbations and their management.
Discuss the topline results from an observational study of pulmonary exacerbations.
Define the relevant clinical endpoints for the design of interventional studies of pulmonary exacerbations.