This session deals with fundamental questions central to our understanding of how the CFTR protein is structured & functions as an anion channel. There are also presentations related to the molecular basis for disease cause by mutations in CFTR & therapeutic strategies to repair such defects.
Discuss the current understanding regarding structure function relationships in CFTR.
Explain molecular defects caused by mutation.
Describe the mechanism of action of emerging interventions targeting defects caused by CFTR mutations.