This session will provide a state-of-the art assessment of factors affecting mucus viscoelasticity & mucus clearance in in vitro & in vivo models of CF. These presentations will focus on the relationship between defective ion transport, fluid secretion & mucus biophysical properties, as well as methods for evaluating mucus transport & potentially normalizing mucus in a CF environment.
Explain effects of ion composition on biophysical properties of mucus.
Describe CF & normal mucus secretion and transport.
Identify pharmacological strategies to promote mucus clearance.