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30th Annual North American Cystic Fibrosis Conference

S01: APP&D: Mucociliary Transport & Ion Flux: Lessons Learned From New Models & New Drugs

Oct 27, 2016 2:00pm ‐ Oct 27, 2016 3:25pm

Standard: $49.99


Mucociliary clearance and airway surface pH are each defined by CFTR and play key roles in CF lung pathophysiology. New data, animal models and CFTR modulating drugs offer unique opportunities to better understand the basic defects causing lung disease in patients. This symposium will review and integrate these data, allowing the participant to better understand the basis of new therapeutic approaches for CF lung disease.

Educational Objectives:
  • Discuss the importance of absorption, secretion and pH in CF lung pathophysiology.
  • Summarize innate immunity in the airways of healthy individuals and of people with CF.
  • Identify promising new therapeutic approaches addressing the basic defects in mucociliary clearance and host defenses in the CF airways.



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