0       0

30th Annual North American Cystic Fibrosis Conference


S02: CFTR: Understanding Missense & Misfolding Mutations in CFTR


Oct 27, 2016 2:00pm ‐ Oct 27, 2016 3:25pm

Standard: $49.99

Description

This symposium aims to provide insights into the mechanisms how the most common CF mutations, categorized by the CFTR2 initiative, influence CFTR structure and function. This will be discussed in light of the CFTR 3D model, with a particular focus on structures of the nucleotide-binding domains (NBDs). Furthermore, this session will also discuss how the cellular proteome may deferentially process CF mutations.

Educational Objectives:
  • Describe the latest data on categorizing the CFTR2 database concerning trafficking, function and clinical manifestations.
  • Explain how CF mutations influence CFTR structure and function using 3D models of CFTR and structures of the NBDs.
  • Identify how mutation-specific interactome directs the fate of CFTR.

Speaker(s):

You must be logged in and own this session in order to post comments.

Print Certificate
Review Answers
Print Transcript
Completed on: token-completed_on
Review Answers
Please select the appropriate credit type:
/
test_id: 
credits: 
completed on: 
rendered in: 
* - Indicates answer is required.
token-content

token-speaker-name
token-index
token-content
token-index
token-content
token-index
token-content
token-index
token-content
token-index
token-content
token-index
token-content
/
/
token-index
token-content