The interplay between CFTR, bacterial infection & airway innate immunity are multiple. Growing evidence also indicates that CFTR plays a key role in directly modulating macrophages & neutrophil function. This symposium will present recent evidence that link CFTR deficiency & infection to abnormal host defenses & hyperinflammation.
Summarize the impact of CFTR function on airway mucosal environment.
Discuss the role of CFTR function on immune cells.
Summarize how Pseudomonas aeruginosa impacts airway inflammation.