31st Annual North American Cystic Fibrosis Conference

W02 - W02: CFTR: CFTR 2017

Nov 2, 2017 9:45am ‐ Nov 2, 2017 11:05am


Description

This workshop focuses on new insights into the biosynthetic pathway of CFTR and highlights recent developments relating to protein structure and function. Additionally, discussions will include evaluation of currently available small molecule-based therapies and their effects on CFTR channel activation across multiple species. Clinical implications of these findings will also be addressed.

Learning Objectives:

  1. Describe novel strategies for the development and functional characterization of CFTR modulators.
  2. Summarize topical advances in CFTR structure and visualization.
  3. Assess efficacy of current CFTR pharmacological correctors and potentiators within various in vitro and in vivo contexts.

Workshop Chair(s):

Workshop Speaker(s):

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