This session will provide an overview of the use of probiotics, acid suppression and pancreatic enzyme replacement therapy in cystic fibrosis. In addition, drug-induced liver injury and the management of elevated liver enzymes with commonly used cystic fibrosis medications will be discussed.
Define drug-induced liver injury, list commonly implicated agents in cystic fibrosis and discuss management of elevated liver enzymes with commonly used cystic fibrosis medications.
Review use of acid suppression in cystic fibrosis, discuss indications for use and use of alternative agents, and appraise the risks vs. benefits of long-term acid suppression.
Describe the pharmacology of pancreatic enzyme replacement therapy and probiotics and appraise the evidence regarding their use for the gastrointestinal manifestations of cystic fibrosis.
Assistant Professor of Clinical Pediatrics,
Indiana Univ. School of Medicine