31st Annual North American Cystic Fibrosis Conference

W21 - W21: APP&D: CF Inflammation: Mechanisms, Treatment & Prevention

Nov 4, 2017 10:30am ‐ Nov 4, 2017 11:50am


Description

This session explores how maladaptive responses of inflammatory cells and mediators may contribute to CF airway disease, and how new interventions targeting these responses could be therapeutic for people with CF.

Learning Objectives:

  1. Describe how pharmacological correction of CFTR modulates inflammatory signaling; discuss the role of IL-17 T cells in P. aeruginosa infection.
  2. Explain the impact of the CF airway milieu on transcriptional regulation of PMNs; learn the interplay between pannexin 1 and inflammatory responses of macrophages.
  3. Discuss metabolic differences between macrophages derived from different regions of the lung.

Workshop Chair(s):

Workshop Speaker(s):

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