The recent surge in both culture-dependent and culture-independent surveys of the lung microbiota underscore the polymicrobial nature of CF lung disease. The challenge now is to understand how interactions between microbial community members and their local environment contribute to disease states. The purpose of this workshop is to highlight recent advances in this area, and to better understand the complex interplay between bacterial communities and the host airway.
Distinguish the structure and function of microbial communities and how their temporal dynamics are linked to disease state.
Describe the contributions of interspecies bacterial interactions to pathogenesis. 3
Discuss recent in vitro and in situ studies of bacterial pathogens and their interactions with host cells.