Alexander Scheffold Ph.D.

The Charité – Universitätsmedizin Berlin

Alexander Scheffold studied Chemistry in Freiburg and Cologne from 1986-1992. During his PhD work at the University of Cologne in the group of Andreas Radbruch he developed new cytometric tools for functional characterization of T cells. From 1997 to 2007 he was an independent group leader at the DRFZ Berlin working on the extrinsic and intrinsic regulation of inflammatory T cell reactions by regulatory T cells and IL-10. From 2008-2011 he was leading a research group on T cell therapy at Miltenyi Biotech where he was responsible for the development of new tools for the identification of human antigen-specific T cells and the development of GMP processes for the generation of clinical T cell transplants. Since 2012 he is professor for cellular immunology at the The Charité – Universitätsmedizin Berlin, Department of Rheumatology and Clinical Immunology, where his group tries to decipher the molecular pathways controlling IL-10 production by T helper cell substes and works on the characterization of antigen-specific effector and regulatory T cells involved in human immune-mediated diseases, such as chronic infectious or inflammatory diseases, allergy or autoimmunity.