Rabindra M. Tirouvanziam Ph.D.

Assistant Porfessor, Emory University

Rabindra Tirouvanziam earned his Bioengineering degree at the Paris Institute of Technology for Life, Food and Environmental Sciences (Agro-Paris Tech, France) in 1994 and his PhD in Developmental Biology, Lung Physiology and Immunology at the College de France and French National Center for Scientific Research (CNRS; Paris, France) in 1998. He then trained as a Postdoctoral Fellow (1999-2004), Research Associate (2004-2008) and Instructor (2008-2011) at Stanford University (CA, USA). He joined Emory University as an Assistant Professor of Pediatrics and faculty in the Immunology and Molecular Pathogenesis graduate program in 2011.Research in his laboratory include patient- and model-based studies in cystic fibrosis (CF), allergy/asthma, and malaria, as well as other disease conditions, focusing on immunology and metabolism. The Tirouvanziam laboratory emphasizes sample collection from patients and animal models using direct, high-content analyses by flow and image cytometry (for cells) and multiplexed ELISA and mass spectrometry (for fluids) to delineate mechanisms of immunity and their relations to chronic disease.In the context of CF, Dr. Tirouvanziam's work has helped redefine the role of neutrophils in CF airway inflammation. Most notably, his group has brought definitive evidence that neutrophils remain viable upon recruitment to the airways of CF patients and undergo profound functional reprogramming. This discovery opens important new avenues for therapeutic development relative to this intractable aspect of CF airway disease.