Matthew E. Siefert Masters of Science

Cincinnati Children's Hospital

Mr. Matthew Siefert received his Master of Science in Zoology in 2013 at Miami University in Oxford, Ohio. As an undergraduate, Matt received an undergraduate research award which allowed him to start his own project characterizing glial cell ensheathment of peripheral nerves in Drosophila larvae. As a Masters candidate, Matt expanded on his undergraduate work in an attempt to characterize the role of glial cells during nervous system remodeling between Drosophila larval and adults stages. He also researched the fate of a subset of larval motor neurons during metamorphosis. From 2014 to 2015, Matt worked as a neurophysiologist at The Nielsen Company conducting neuro-market research. There he analyzed consumers' subconscious emotional responses, memory activations, and attentional patterns. Since leaving The Nielsen Company in mid 2015, Matt has worked at Cincinnati Children's Hospital Medical Center in the Ziady Lab. His current research focuses on examining the interaction between the antioxidant response element (ARE) and inflammatory signaling, primarily Nrf2 dysfunction in cystic fibrosis. He also researches the development and characterization of DNA nanoparticles for nonviral gene therapy in the lung, liver, and brain.