Patrick Flume is a Professor of Medicine and Pediatrics at the Medical University of South Carolina and has been part of the MUSC program since 1993. He serves as the Powers-Huggins Endowed Chair for Cystic Fibrosis and oversees a rapidly growing Cystic Fibrosis Center, including the largest adult CF program in South Carolina. He is recognized by the national and international CF community having served on the CF Foundation Center Committee, the Adult Care Consensus Committee, and the Advisory Task Force on Adult Issues, the Professional Education Committee, the European CF Society's Best Practices committee, and as founding co-chair of the CF Foundation's Pulmonary Practice Guidelines Committee. He is the Deputy Editor for the Journal of Cystic Fibrosis. His also leads a very busy clinical research program for CF. Many of these studies are related to new drug and therapy development for patients with CF, but he also has an interest in determining optimal management of pulmonary exacerbations and is the co-PI in the STOP trials, aimed at identifying optimal treatments for exacerbations.