John W. Hanrahan B.Sc.,Ph.D.

Professor, McGill University

Dr. Hanrahan received his PhD in 1982 from the University of British Columbia in Vancouver, B.C. Canada. As a graduate student he studied the mechanism of chloride and potassium transport across insect epithelia using a variety of electrophysiological methods. He completed post-doctoral studies in the Department of Cellular and Molecular Physiology at Yale Univ. Sch. Medicine from 1982-1985, supported by fellowships from NSERC/NATO and the Medical Research Council of Canada. At Yale he carried out noise analysis and patch clamp studies of anion channels in the rabbit urinary bladder epithelium. In 1986 Dr. Hanrahan joined the Department of Physiology at McGill University as Assistant Professor, where he has remained as Associate and Full Professor. Dr. Hanrahan began studying chloride channels in cystic fibrosis soon after arriving at McGill and became an off-site member of the Research Development Program based at the Hospital for Sick Children in Toronto. Dr. Hanrahan helped identify the ion channel that is defective in CF and establish the CFTR gene product as that anion channel. He is the founding director of the CF Translational Research centre (CFTRc) and the primary airway cell biobank (PACB) at McGill. His laboratory remains focused on basic aspects of cystic fibrosis and correctors that rescue the misfolded mutant protein.