Hsiao Chan Ph.D.

Professor Hsiao Chang CHAN Li Ka Shing Professor of Physiology Director, Epithelial Cell Biology Research Centre School of Biomedical Sciences, Faculty of Medicine The Chinese University of Hong Kong Professor Hsiao Chang Chan received her B. S. in Bioengineering (1983) and Ph.D. in Biophysics (1988) from the University of Illinois, Urbana-Champaign (USA) and went on her postdoctoral training at the University of Chicago (1989-1993). She joined the Department of Physiology, Faculty of Medicine at the Chinese University of Hong Kong in 1993 and is currently Li Ka Shing Professor of Physiology at the School of Biomedical Sciences. She also holds visiting professorships or honorary positions at over 20 institutions / universities in mainland China. Professor Chan has broad interests in epithelial cells related interdisciplinary research, including reproductive tract functional genomics, epithelial transport and signaling mechanisms, epithelial-derived cancer metastasis, epithelial differentiation of stem cells as well as epithelial-mediated mucosal immune defense mechanisms. She has been the driving force for promoting multidisciplinary collaborations in epithelial related research nationwide and is the founding Director of the Epithelial Cell Biology Research Center, first of its kind ever found in China. She has contributed significantly to a number of important discoveries, including a cell shrinkage-activated cation channel (Science 1992); -defensins in defending male fertility (Science 2001, Nature Cell Biology 2004, Science Translational Medicine 2014), the role of CFTR in male and female fertility and infertility (Nature Cell Biology 2003, PNAS 2007) and insulin secretion (Nature Communication 2014); ENaC in signaling mechanism underlying embryo implantation (Nature Medicine 2012). She has received a number of prestigious awards including the National Natural Sciences Award of China (1997, 2008), Distinguished Young Investigator (National Science Foundation of China, 2000), Croucher Senior Research Fellowship (2007) and Chang Jiang Scholars Achievement Award (2008). Professor Chan serves on numerous international editorial boards and has also been invited to review grants for a number of funding agencies worldwide, including WHO, Wellcome Trust (UK), German Cystic Fibrosis Association, Italian Telethon Foundation, National Natural Science Foundation of China, National Science Foundation (USA), Experimental and Translational Medicine Research, Chief Scientist Office of Scotland, US-Israel Binational Science Foundation.


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