Margarida Amaral Ph.D.

Full Professor of Biochemistry/ Molecular Biology, BioISI

Margarida Amaral is Full Professor of Biochemistry/ Molecular Biology at the Faculty of Sciences, University of Lisboa (Portugal) and Coordinator of BioISI - Biosystems & Integrative Sciences Institute. MDA is alumna of EMBL-European Molecular Biology Laboratory (2008-10; 2016) and IGC - Gulbenkian Institute of Science alumna (1983-1993). Research: Molecular and cellular mechanisms of the genetic disease Cystic Fibrosis. My lab has its major focus on the molecular and cellular mechanisms of biogenesis, traffic and degradation of normal and mutant protein CFTR, which when mutated causes the genetic disease Cystic Fibrosis (CF). To understand CF mechanisms globally we use transcriptomics, proteomics and functional genomics (functional siRNA screens). Our results translate into the clinic for better CF diagnosis, prognosis and personalized therapies. Author of 118 international publications (average citations per article: 24.2); Researcher ID: E-5748-2012. Awards & Honours: member of EMBO - European Molecular Biology Laboratory ; member of the Portuguese Academy of Sciences (2014); Pfizer Award for Basic Biomedical Research (2013); Annual Award of European Cystic Fibrosis Society (2010). Other: Elected member of the Board of ECFS-European Cystic Fibrosis Society and associate editor of J Cystic Fibrosis (Elsevier) and Scientific Reports (Nature Group). Former SAB member of the Cystic Fibrosis Trust (UK) and of the German Cystic Fibrosis Foundation