Charles Esther, Jr. M.D., Ph.D.

Dr. Esther obtained his MD and PhD degrees from Emory University in 1998 then completed Pediatric residency and Pediatric Pulmonology fellowship at the University of North Carolina at Chapel Hill. Since completing training in 2004, he has remained on faculty at the UNC Chapel Hill, providing clinical care to children with cystic fibrosis and other disease while maintaining active research laboratory and serving as director of the Pediatric Pulmonology Fellowship Training Program. His research has focused on understanding the pathophysiology of airways diseases, especially early CF lung disease. To this end, he has utilized mass spectrometric metabolomic approaches to discover novel relationships between airway metabolic pathways and lung disease, with a goal of identifying both new biomarkers and new therapeutic targets. In addition, he has studied the relationships between various respiratory pathogens, in particular nontuberculous mycobacteria, and clinical outcomes in CF. He has published extensively and been supported by grants from the NIH, CF Foundation, and industry.