Christine Chan M.D.

Children's Hospital Colorado

Dr. Chan is a pediatric endocrinologist at Children;s Hospital Colorado. She received her MD from the University of California Irvine in 2006 and completed her pediatric endocrinology fellowship at the University of Colorado in 2012 after which she joined the endocrine faculty at Children's Hospital Colorado. Her primary area of interest is diabetes clinical research, specifically in cystic fibrosis-related diabetes (CFRD). Her current research project investigates the role of continuous glucose monitoring (CGM) in the screening and management of CFRD. Her fellowship research examied CGM and its relationship to the common diabetes screening tests hemoglobin A1c (HbA1c) and oral glucose tolerance test (OGTT) in obese youth at risk for type 2 diabetes. Although HbA1c and OGTT are often used interchangeably, an important finding of her work was that CGM revealed the strengths of each screening test to reflect different components of free-living glycemia. She subsequently became interested in CFRD, specifically in understanding the significance of early glycemic abnormalities that traditional CFRD screening tests may overlook. She is challenged by the high prevalence of early glycemic abnormalities in CF and interested in determining whether these findings correlate with lasting health consequences. The overall goal of her research is to determine if CGM abnormalities have a role in predicting decline in key-CF clinical outcomes and to pave the way for future glucose-based interventional trials to prevent CF clinical decline.