Mitchell L. Drumm Ph.D.

Professor, Case Western Reserve Univ.

Dr. Drumm received his B.S. in genetics from The Ohio State University in 1983 and his Ph.D. in Human Genetics from the University of Michigan in 1990. His doctoral degree was earned in the laboratory of Francis Collins, M.D., Ph.D., with whom he was a co-discoverer of the gene that causes cystic fibrosis (CF). Dr. Drumm continues to work on CF and joined the faculty at Case Western Reserve University in 1992 as an assistant professor in the Departments of Pediatrics and Genetics and now holds the rank of professor in both departments. Dr. Drumm’s early work showed that CF cells could be “corrected” by introduction of a normal copy of the CF gene and laid the groundwork for studies in CF gene therapy. He also demonstrated that the most common mutation found in CF could be manipulated to exhibit ion channel activity and pioneered the search for drugs that can correct the underlying channel defect in CF. He has authored over 90 peer-reviewed manuscripts and several book chapters on cystic fibrosis and holds three patents relevant to the disease as well. In 2007, Dr. Drumm was appointed as Director of Basic Research of the Willard A. Bernbaum Cystic Fibrosis Research Center and in 2011 the Vice Chair of Research in the Department of Pediatrics. His research program continues to focus on the genetics of CF, but he also utilizes mouse genetics to better understand the disease and explore treatment strategies. Dr. Drumm also serves as an advisor to several cystic fibrosis research centers, reviews grant applications for the National Institutes of Health and serves numerous roles for the Cystic Fibrosis Foundation, including co-chair of their Research and Research Training Committee. In 2015 he was appointed the inaugural recipient of the Connie and Jim Brown Professor in Cystic Fibrosis Research at Case Western Reserve University.

Appearances