Dr McNally graduated from the UCD school of Medicine in 1998. He completed his paediatric medical training in Ireland and subsequently entered a 2 year Masters in Medicine program in cystic fibrosis (CF) lung disease in the National Children's Hospital Tallaght and the Royal College of Surgeons in Ireland. Dr McNally underwent pedeiatric pulmonary fellowship training at the Children's Hospital of Philadelphia from 2007 to 2009. He was appointed as a consultant in Paediatric Respiratory Medicine at Our Lady's Children's Hospital, Dublin in 2009. He was appointed a clinical senior lecturer in Paediatrics at Trinity College in 2011 and is a principle investigator and director of CF research at the National Children's Research Centre. Dr McNally is head of Respiratory Medicine OLCHC in Dublin, and is clinical lead for Paediatric Respiratory Medicine in the Dublin Paediatric Hospitals. He is a member of the medical and scientific council of CF Ireland and the Scientific Advisory Committee of the CF Registry of Ireland. Dr McNally is a member of the working group of the National Clinical Programme for Cystic Fibrosis and is a member of the advisory board for the National Clinical Programme for Paediatrics. His major research interest is in early CF lung disease. With his colleague, Dr Barry Linnane, he established the SHIELD CF programme (Study of Host Immunity and Early Lung Disease in CF) in 2010, an ambitious long term translational research study designed to examine the causes of early lung disease preschool children born with CF in Ireland. Dr McNally is local principle investigator for a number of clinical trials in CF and a reviewer for frontiers in paediatric pulmonology.